The Ballon d’Or winner was substituted after half an hour during Sunday’s 2-1 Ligue 1 defeat against Paris FC “as a precaution after experiencing some discomfort in his right calf,” PSG said in a statement.
“Dembele will be having treatment over the next few days,” the club added.
The 29-year-old did not appear to be struggling when he left the field and boarded the team bus after the match without limping.
“I think it is just due to fatigue,” coach Luis Enrique told the press on Sunday.
“It has been a tricky end to the season but now we have two weeks to prepare for the biggest match in our history.”
The former Barcelona player has suffered numerous physical setbacks this season, particularly thigh and calf issues.
Meanwhile, Achraf Hakimi resumed individual training on Saturday after a thigh problem, as did Willian Pacho, Nuno Mendes, and Lucas Chevalier.
All three were unavailable for Sunday’s match against Paris FC.
PSG clinched a fifth straight French title, and a record-extending 14th overall, with a 2-0 win over nearest challengers Lens last Wednesday.
Luis Enrique’s side face Arsenal in Budapest on May 30, when they will attempt to retain the European crown they won for the first time in the club’s history last season.
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